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Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children — IPCOM  

Congenital Heart Disease Clinical Trial

Official title:
Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children

Clinical Trial Summary

Interventional Trial to determine the Effect of different PEEP levels on Cardiac output and right-ventricular function in mechanically ventilated children < 5 years of age with congenital heart disease.

Clinical Trial Description

Different PEEP-levels will be applied during invasive mechanical ventilation to describe Cardio-pulmonary interactions in children with congenital heart disease (CHD). An additional trial with the same study protocol is planned in a cohort of children with primarily pulmonary disease without CHD after completion of this trial. Esophageal pressure-monitoring, Ultrasound, respiratory mechanics and electrical impedance tomography will be used ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06270485
Study type Interventional
Source Charite University, Berlin, Germany
Contact Jan Clausen, MD
Phone 004917620808764
Email jan-christoph.clausen@dhzc-charite.de
Status Recruiting
Phase N/A
Start date November 27, 2023
Completion date June 2025
View Details
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