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NCT06241079 Clinical Trial

Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma Clinical Trial

Official title:
Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06241079
Other study ID # bc2023183
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 31, 2003
Est. completion date February 1, 2023

Study information
Verified date January 2024
Source Tianjin Medical University Cancer Institute and Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The goal of this multicenter retrospective cohort study is to evaluate the impact of different pathological regression types on survival and recurrence patterns, with a particular focus on ypT0N+ patients in patients with esophageal squamous cell carcinoma. The main questions it aims to answer are the survival and recurrence patterns among the different pathological regression types in patients with esophageal squamous cell carcinoma after neoadjuvant chemoradiotherapy.

Recruitment information / eligibility
Status Completed
Enrollment 582
Est. completion date February 1, 2023
Est. primary completion date April 28, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - histologically confirmed potentially resectable ESCC, clinical stage T1-4N0-1M0 (stage I-III) according to the American Joint Committee on Cancer 6th edition staging criteria. Exclusion Criteria: - incomplete surgical resection, two-dimensional radiotherapy, and incomplete clinical data.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• non-intervention
non-intervention

Locations
Country Name City State
n/a

Sponsors (3)
Lead Sponsor Collaborator
Tianjin Medical University Cancer Institute and Hospital Chinese Academy of Medical Sciences, Sichuan Cancer Hospital and Research Institute

Outcome
Type Measure Description Time frame Safety issue
Primary Overall survival the time from the date of surgery to death or last follow-up (2023.01.31) From date of surgery until the date of death from any cause or last follow-up, assessed up to 10 years.
See also
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