Preoperative Nutritional Status and Postoperative Acute Kidney Injury

Postoperative Acute Kidney Injury Clinical Trial

Official title:

Prognostic Significance of Preoperative Nutritional Status for Postoperative Acute Kidney Injury in Elderly Patients Undergoing Major Abdominal Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05945940
• Other study ID #: TJH-20230608A
• Status: Completed
• Start date: July 20, 2023
• Est. completion date: July 30, 2023

Study information

• Verified date: October 2023
• Source: Tongji Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

There is a high prevalence of postoperative acute kidney injury (AKI) in patients who undergo intra-abdominal surgery, and it is particularly common in the elderly. Identifying high-risk patients for postoperative AKI early can facilitate the development of preventive and therapeutic management strategies.

The goal of this retrospective study is to investigate the predictive value of preoperative nutritional status, as measured by three scoring systems - the geriatric nutritional risk index (GNRI), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score - on postoperative AKI in elderly patients undergoing major abdominal surgery.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2977
• Est. completion date: July 30, 2023
• Est. primary completion date: July 30, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 65 Years to 100 Years

Eligibility

Inclusion Criteria:

1. aged = 65 years

2. intra-abdominal procedures including gastric, colorectal, pancreatic, prostate, and urinary bladder surgeries, as well as abdominal exploration.

3. surgery duration lasting longer than 2 hours.

Exclusion Criteria:

1. patients with an American Society of Anesthesiologists (ASA) physical status V.

2. those with concurrent cardiac or renal surgeries.

3. those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis).

4. those did not have sufficient data required for nutritional evaluation or AKI evaluation.

Related Conditions & MeSH terms

• Acute Kidney Injury
• Postoperative Acute Kidney Injury
• Wounds and Injuries

Intervention

Other:
• no intervention
no intervention

Locations

Country	Name	City	State
China	Rao Sun	Wuhan

Sponsors (1)

Lead Sponsor	Collaborator
Rao Sun

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postoperative acute kidney injury	In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.	Within 7 days after surgery