Clinical Trial Details
— Status: Not yet recruiting
Administrative data
| NCT number |
NCT05813002 |
| Other study ID # |
REC-22-06-04-S |
| Secondary ID |
|
| Status |
Not yet recruiting |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
April 2023 |
| Est. completion date |
May 2023 |
Study information
| Verified date |
April 2023 |
| Source |
University of Sharjah |
| Contact |
Ibrahim M [imoustafa], Professor |
| Phone |
+971502180024 |
| Email |
iabuamr[@]sharjah.ac.ae |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
the main objective of this study is to investigate if different neurodynamic test sequencing
of the median nerve has a different impact on median nerve root function. We hypothesized
that the order of median nerve neurodynamic movements would influence peak-to-peak amplitude
and latency.
Description:
Neurodynamic concept is used clinically to normalize nerve mobility. It has been manifested
in previous studies that neurodynamics have increased mobility by floss like movement of the
nerve. Whereas in other studies it has been concluded that neurodynamic techniques has an
effect in decreasing fibrous and adhesions between neural tissues and the surrounding tissues
therefore giving an outcome of improved infrafasicular gliding.
The upper limb neurodynamic test has an effect to alter the mechanical loads on the nerve by
changing its dimensions. For neurodynamic to be more effective, it requires a certain
sequence.
The different order of movements will induce different duration of tension in which it will
influence the nerve root function, which is needed to be investigated to check for the
effectiveness. A previous study has found that the difference of sequence on median nerve,
had caused a change on the distribution of the sensory response on the asymptomatic
participants. The sensory responses were more prevalent during the neurodynamic of the median
nerve when it was applied from a distal to proximal sequence . One of the main purposes of
the order of sequences is to add more strain to the nerve segment to increase the sensitivity
of the test.
Clinically it has been assumed that the different order of movements could possibly influence
the level of strain on a certain nerve segment. When the standard sequence was compared with
the distal-to-proximal sequence for the median nerve, there was no physiological difference
obtained at the end of the test. In comparison, there was a larger strain in the
distal-to-proximal sequence in comparison to the proximal-to-distal sequence observed.
However, the longitudinal excursion collected data indicated that the start and end positions
for all the three sequences were alike.
In terms of neurophysiological outcomes, in this study we will use the dermatomal
somatosensory evoked potential as a primary outcome due to its reliability in comparison with
other physiological outcomes. There is a literature gap in regard to the effect of the order
of sequence on the median nerve on the nerve root function and this is what the study will
focus on. We hypothesized that the order of movements of the median nerve neurodynamic will
influence the peak-to-peak amplitude and the latency.
