Vitreous Hyper Reflective Dots in Association With Pseudophakic Cystoid Macular Edema

Cystoid Macular Edema Following Cataract Surgery Clinical Trial

Official title:

Prospective Analysis of the Correlation Between Hyperreflective Dots in the Vitreous Body and the Appearance of a Pseudophakic Cystoid Macular Edema

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05811182
• Other study ID #: 30-273 ex 17/18
• Status: Completed
• Start date: July 1, 2018
• Est. completion date: March 1, 2020

Study information

• Verified date: April 2023
• Source: Medical University of Graz
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this study is to assess the association between vitreous hyper-reflective dots (VHD) and the macular thickness changes following uneventful phacoemulsification. In this prospective study the investigators performed optical coherence tomography (OCT) imaging in patients undergoing cataract surgery preoperatively and postoperatively after 1 week, 1 month and 3 months and analyzed the OCTs for VHDs. The investigators then measured the macular thickness in patients with VHDs and without VHDs and correlated the macular thickness with the number of VHDs.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 97
• Est. completion date: March 1, 2020
• Est. primary completion date: March 1, 2020
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients undergoing cataract surgery

• minimum age 18 years

• phacoemulsification technique

• subsequent implantation of a monofocal hydrophobic acrylic intraocular lens

Exclusion Criteria:

• intraoperative complications including capsule rupture with or without anterior vitrectomy

• iris bites

• previous interventions including vitrectomy

• glaucoma surgery

• exudative or dry age-related macular degeneration

• presence of diabetes

• history or presence of retinal vein occlusion or uveitis

• epiretinal glioses

Related Conditions & MeSH terms

• Cataract
• Cystoid Macular Edema Following Cataract Surgery
• Edema
• Macular Edema

Locations

Country	Name	City	State
Austria	Medical University of Graz	Graz	Styria

Sponsors (1)

Lead Sponsor	Collaborator
Medical University of Graz

Country where clinical trial is conducted

Austria, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	vitreous hyperreflective dots	Change of correlation between occurrence of vitreous hyperreflective dots and the macular thickness	preoperatively until 3 months postoperatively