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Satralizumab in Aneurysmal Subarachnoid Hemorrhage — SASH  

Aneurysmal Subarachnoid Hemorrhage Clinical Trial

Official title:
A Phase 1 Clinical Trial of Satralizumab as a Treatment for Aneurysmal Subarachnoid Hemorrhage

Clinical Trial Summary

In this study, satralizumab will be administered to see whether satralizumab is safe in patients with a burst brain aneurysm and if it may prevent strokes in patients with a burst brain aneurysm.

Clinical Trial Description

SASH is a prospective single-arm, single-center, open-label Phase 1 trial of satralizumab 120mg subcutaneous Day 0 and Day 14 in subjects with Hunt Hess grade 1-3, Fisher score 3 aneurysmal subarachnoid hemorrhage and an external ventricular drain or lumbar drain. The trial is designed to demonstrate safety and to detect a signal that satralizumab prevents delayed cerebral ischemia in these patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05727657
Study type Interventional
Source University of Florida
Contact Brian Hoh, MD
Phone 352-273-9000
Email brian.hoh@neurosurgery.ufl.edu
Status Not yet recruiting
Phase Early Phase 1
Start date June 1, 2024
Completion date December 1, 2026
View Details
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