Anticoagulants and Bleeding Disorders Clinical Trial
Official title:
Safety of Anticoagulant Therapy After Tissue Glue for Gastric Varices
This study aimed to clarify the safety of anticoagulant therapy after glue injection for cirrhotic variceal bleeding patients with portal vein thrombosis.
Acute esophagogastric varices bleeding is a common gastroenterological emergency. And the bleeding from ruptured gastric varices is massive and difficulty to stop, even after aggressive pharmacological and conservative treatment. Even after aggressive pharmacological and conservative treatment, maintaining patients without bleeding for a long time is still a challenging clinical problem. Endoscopic tissue adhesive injection is recommended by many international guidelines for acute hemostasis and secondary prevention of gastric variceal bleeding. However, postoperative glue extrusion is inevitable, and the the rebleeding caused by glue ulcers is a problem that is often faced in clinical work. In patients with portal vein thrombosis, the need for anticoagulation and the choice of anticoagulant drugs need to be carefully evaluated in terms of risk and benefit, as the dual conflicts of thrombosis and anticoagulation are involved. At present, there is no in-depth study or consensus on the effect of anticoagulation on rebleeding after glue injection in patients with portal vein thrombosis. This study is of great significance for the treatment and prognosis of patients with gastric varices combined with portal vein thrombosis. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04517461 -
Coagulation and Vitamin K in Head and Neck Microvascular Free Flap Surgery
|
||
| Terminated |
NCT03296033 -
Residual Anti-Xa Activity After Last Treatment Dose of Enoxaparin
|
Phase 4 | |
| Recruiting |
NCT05123326 -
Global Coagulation Assessment in Portal Vein Thrombosis and Budd-Chiari Syndrome
|
||
| Completed |
NCT04074980 -
Evaluation of the Accuracy of INR Results From Patients Taking Phenprocoumon as Anticoagulant When Measured Using the Lumiradx INR Test
|
N/A | |
| Completed |
NCT04505475 -
Oral Surgery in Patients Taking Direct Oral Anticoagulants
|
||
| Not yet recruiting |
NCT05997914 -
Storytelling for Reducing Gap in Anticoagulation Use in African Americans With Atrial Fibrillation
|
N/A | |
| Recruiting |
NCT04329390 -
MAC Project, Monitoring of AntiCoagulant Therapies (MAC)
|
||
| Completed |
NCT03112525 -
DAPHNE Study: Direct Anticoagulant PHarmacogeNEtic
|
||
| Recruiting |
NCT03760874 -
Atrial Fibrillation Research Database
|
||
| Recruiting |
NCT04046029 -
Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.
|
Phase 4 | |
| Completed |
NCT04444700 -
A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 Pandemic
|
Phase 3 | |
| Terminated |
NCT03566303 -
Rivaroxaban vs Warfarin in Patients With Metallic Prosthesis
|
Phase 2/Phase 3 | |
| Not yet recruiting |
NCT04128254 -
A Prospective Study in Chinese Patients With Lower Extremity Ankle Fracture of Oral Anticoagulants to Prevent Venous Thromboembolism (VTE)
|
Phase 4 | |
| Recruiting |
NCT05946863 -
Caudal Block & Hip Fracture Surgery in Anticoagulated Patient
|
||
| Recruiting |
NCT05946850 -
Caudal Analgesia & Anticoagulated Patient
|
||
| Completed |
NCT06269302 -
Comparison of the Effect of Warfarin and Direct Oral Anticoagulants
|
||
| Recruiting |
NCT04676880 -
Left Atrial Appendage Occlusion for AF Patients Unable to Use Oral Anticoagulation Therapy
|
N/A | |
| Completed |
NCT05224388 -
Evaluating Dose Regimen of Intravenous Unfractionated Heparin and Low Molecular Weight Heparin in Critical Ill Patients Versus Critical Ill COVID-19 Patients Using Anti-Xa Levels.
|
||
| Completed |
NCT03871283 -
Anticoagulation and Antiplatelet Management During Perioperative Period
|
||
| Completed |
NCT03232398 -
Apixaban Versus Warfarin in Patients With Left Ventricular (LV) Thrombus
|
Phase 3 |