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Empagliflozin in Pulmonary Arterial Hypertension — Emphower PoC  

Idiopathic Pulmonary Arterial Hypertension Clinical Trial

Official title:
Feasibility Study of Empagliflozin as Treatment for Idiopathic Pulmonary Arterial Hypertension

Clinical Trial Summary

The aim of the study is to determine whether conducting a randomized placebo-controlled clinical trial is feasible, safe for the patient and whether the treatment is well tolerated in patients with idiopathic pulmonary arterial hypertension.

Clinical Trial Description

This study is designed as a prospective, single-center, phase IIa, single-arm, open-label, interventional proof-of-concept trial in patients diagnosed with idiopathic pulmonary arterial hypertension (IPAH) who are currently on stable therapy. Patients will be administered a once-daily oral dose of 10 mg empagliflozin for a duration of 12 weeks along with standard treatment. The primary objective of this study is to assess safety and tolerability of empagliflozin and to assess whether a potential future randomized, double-blind, placebo-controlled study is feasible. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05493371
Study type Interventional
Source Amsterdam UMC, location VUmc
Contact Harm Jan Bogaard, Prof. dr.
Phone +31204444782
Email hj.bogaard@amsterdamumc.nl
Status Recruiting
Phase Phase 2
Start date March 1, 2023
Completion date November 1, 2024
View Details
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