Mechanical Cardiopulmonary Resuscitation During Treatment of Acute Respiratory Failure Through Extracorporeal Membrane Oxygenation.

Venovenous Extracorporeal Membrane Oxygenation Clinical Trial

Official title:

Mechanical Cardiopulmonary Resuscitation During Treatment of Acute Respiratory Failure Through Extracorporeal Membrane Oxygenation.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05342363
• Other study ID #: CPR during VV-ECMO
• Status: Completed
• Start date: June 1, 2022
• Est. completion date: August 1, 2023

Study information

• Verified date: August 2023
• Source: Goethe University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In-hospital cardiovascular arrest is associated with poor outcome despite prompt treatment and optimal on-site resources. The population of patients treated by venovenous extracorporeal membrane oxygenation (vv-ECMO) due to pulmonary failure is a very challenging group of patients. To date, the frequency, causes and outcome of cardiovascular arrest in these patients have not been studied. We are aiming to conduct a retrospective observational study of all vv-ECMO patients treated at our ARDS centre.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 117
• Est. completion date: August 1, 2023
• Est. primary completion date: May 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

Patients treated with veno-venous extracorporeal membrane oxygenation (vv-ECMO) due to respiratory failure during acute respiratory distress syndrome (ARDS). Exclusion Criteria: Patients treated with veno-arterial extracorporeal membrane oxygenation (va-ECMO)

Related Conditions & MeSH terms

• Respiratory Insufficiency
• Venovenous Extracorporeal Membrane Oxygenation

Locations

Country	Name	City	State
Germany	University Hospital Frankfurt	Frankfurt	Hessen

Sponsors (1)

Lead Sponsor	Collaborator
Goethe University

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Survival of mechanical cardiovascular resuscitation	Survival of mechanical cardiovascular resuscitation	During the intensive care stay ( usually between 2 and 8 weeks)
Secondary	Incidence of cardiovascular resuscitation i	Incidence of cardiovascular resuscitation in patients treated with venovenous extracorporeal membrane oxygenation.	During the observation period 2019-2022
Secondary	Complications of resuscitation treatments	Complications of cardiovascular resuscitation in patients treated with venovenous extracorporeal membrane oxygenation	During the intensive care stay ( usually between 2 and 8 weeks)