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Immune System Modulation and Outcome in High-risk cSCC Treated With Surgery and Radiotherapy — HR-cSCC  

Squamous Cell Carcinoma of the Skin Clinical Trial

Official title:
Immune System Modulation and Outcome in High-risk Cutaneous Squamous Cell Carcinoma Treated With Surgery and Radiotherapy: a Prospective Study

Clinical Trial Summary

Treatment with adjuvant radiotherapy modulates immune system in many diseases as witnessed by dynamic changes of humoral and cellular immunity. Moreover, the persistent lymphopenia after radiation therapy is a negative prognostic factor. This study is aimed to explore the changes in immune-cell populations during radiotherapy given as adjuvant treatment for high-risk cutaneous squamous cell carcinomas and to correlate them with patient's outcome.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05246228
Study type Observational
Source Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Contact Aldo Roccaro, MD
Phone +39 0303996851
Email coordinamento.ricerca@asst-spedalicivili.it
Status Not yet recruiting
Phase
Start date March 1, 2022
Completion date December 30, 2025
View Details
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