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Clinical Trial Summary

The investigators hypothesize that nivolumab combined with neoadjuvant chemoradiotherapy (CRT) is safe and effective in patients with locally advanced esophageal squamous cell carcinoma (LAESCC).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05130684
Study type Interventional
Source National Taiwan University Hospital
Contact Ta-Chen Huang, MD
Phone +886223123456
Email e360215@gmail.com
Status Recruiting
Phase Phase 2
Start date February 22, 2021
Completion date March 1, 2024

See also
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Recruiting NCT05520619 - Combination of Tislelizumab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-002) Phase 2
Recruiting NCT04602013 - Sintilimab Injection Combined With Concurrent CCRT in Locally Advanced Esophageal Squamous Cell Carcinoma Phase 2
Not yet recruiting NCT05522894 - AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCC Phase 2
Active, not recruiting NCT03914443 - A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal Carcinoma Phase 1
Not yet recruiting NCT06426797 - Neoadjuvant Cadonilimab Combined With Anlotinib in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma Phase 2
Active, not recruiting NCT06342167 - Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell Carcinoma Phase 2
Recruiting NCT06187597 - Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007) Phase 2
Not yet recruiting NCT04888403 - Exploring the Safety and Effectiveness of Toripalimab Combined With Neoadjuvant Radiotherapy and Chemotherapy in the Locally Advanced Esophageal Squamous Cell Carcinoma Phase 2
Recruiting NCT03917966 - The Phase II Trial of SHR-1210 Combined With Preoperative Chemotherapy or Apatinib for Locally Advanced ESCC Phase 2
Not yet recruiting NCT06356688 - A Clinical Study on the Efficacy and Safety of Paclitaxel Polymer Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma Phase 2