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Clinical Trial Summary

The aim of this study is to evaluate the efficacy of Peribioma Toothpaste and Mousse for home oral care in patients with Diabetes Mellitus Type 1. Patients will undergo a professional oral hygiene procedure, followed by irrigation with ozonized water. Patients will be randomly divided into two groups: - Trial Group: patients will use Peribioma Toothpaste and Mousse for home oral care - Control Group: patients will use standard toothpastes for home oral care. The variations of the following indices will be evaluated at the baseline, after 3 and 6 months: glycosylated hemoglobin (HbA1c) , Clinical Attachment Level (CAL), Probing Pocket Depth (PPD) and Bleeding on Probing (BoP).


Clinical Trial Description

The aim of this study is to evaluate the efficacy of Peribioma Toothpaste and Mousse for home oral care in patients with Diabetes Mellitus Type 1. Patients who respond to eligibility criteria and that will sign the informed consent will undergo a professional oral hygiene procedure; then, ozonized water (aquolab) will be used to irrigate periodontal pockets for 1 minute. Then, patients will be randomly divided into two groups: - Trial Group: patients will use Peribioma Toothpaste and Mousse for home oral care until the end of the study; - Control Group: patients will use standard toothpastes for home oral care until the end of the study. Changes in the following indices will be evaluated at the baseline, after 3 and 6 months: glycosylated hemoglobin (HbA1c) , Clinical Attachment Level (CAL), Probing Pocket Depth (PPD) and Bleeding on Probing (BoP). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04865809
Study type Interventional
Source University of Pavia
Contact Andrea Scribante, DDS, PhD
Phone +39 0382516223
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date April 28, 2021
Completion date October 30, 2021

See also
  Status Clinical Trial Phase
Completed NCT02845024 - The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus N/A
Completed NCT02735837 - The Effect of Topical Doxycycline Gel on HbA1c in Patients With Type 2 Diabetes Mellitus(DM) ® Phase 2/Phase 3