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Clinical Trial Summary

This Phase II, randomized, open-label, multicenter study will evaluate the efficacy and safety of giredestrant compared with physician's choice of endocrine monotherapy in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer who have received one or two prior lines of systemic therapy in the locally advanced or metastatic setting.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Breast Neoplasms
  • Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer

NCT number NCT04576455
Study type Interventional
Source Hoffmann-La Roche
Contact
Status Active, not recruiting
Phase Phase 2
Start date November 27, 2020
Completion date June 27, 2025