The Learning Effects of Task-priority Strategy on Dual-task Weight Shifting and Brain Plasticity in Patients With Parkinson's Disease

Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease Clinical Trial

Official title:

The Learning Effects of Task-priority Strategy on Dual-task Weight Shifting and Brain Plasticity in Patients With Parkinson's Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04288024
• Other study ID #: 201907085RIND
• Status: Completed
• Phase: N/A
• Start date: February 25, 2020
• Est. completion date: June 22, 2020

Study information

• Verified date: February 2020
• Source: National Taiwan University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

(1) postural and suprapostural performance of a dual task would be differently affected by the strategy of task prioritization and (2) the cortical activation is different according to attentional focus strategies.

Description:

These hypothesis would be tested by gait performance, suprapostural accuracy and relative power spectrum of EEG.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 28
• Est. completion date: June 22, 2020
• Est. primary completion date: June 22, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years to 85 Years

Eligibility

Inclusion Criteria:

• 1. modified H-Y stage II-III Parkinson's disease 2. No other diseases 3. Non-demented PD 4. Non-tremor PD

Exclusion Criteria:

• None

Related Conditions & MeSH terms

• Parkinson Disease
• Postural and Suprapostural Performance During Dual Tasking in Patients With Parkinson's Disease

Intervention

Behavioral:
• Weight-shifting training
Postural task: Participants are standing with their weak side on the force plate. During the task, they wight-shift from side to side ranging from 10 to 90 percent of their body weight. Suprapostural task: Participants hold a tray with their arms beside the body, 90 degrees of elbow flexion. They rotate the tray left and right for 45 degrees respectively. During their task, participants should weight-shift and rotate the tray at the same time.

Locations

Country	Name	City	State
Taiwan	National Taiwan University	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	EEG relative power in the delta band	postural and suprapostural performance of a dual task	60 minutes
Primary	EEG relative power in the theta band	postural and suprapostural performance of a dual task	60 minutes
Primary	EEG relative power in the alpha band	postural and suprapostural performance of a dual task	60 minutes
Primary	EEG relative power in the beta band	postural and suprapostural performance of a dual task	60 minutes
Primary	EEG relative power in the gamma band	postural and suprapostural performance of a dual task	60 minutes
Primary	COP trajectory recorded from the force plate	performance of the postural task	60 minutes
Primary	Angles from inclinometer	performance of the suprapostural task	60 minutes
Secondary	Gait velocity from GAITRite	gait performance	5 minutes
Secondary	Cadence from GAITRite	gait performance	5 minutes
Secondary	Mean step length from GAITRite	gait performance	5 minutes
Secondary	Step-to-step variability from GAITRite	gait performance	5 minutes