Benefits of a Capsules of Moringa Oleifera and Stevia Rebaudiana Bertoni in Patients With Type 2 Diabetes Mellitus Before and After 45 Days of add-on Therapy Clinical Trial
Official title:
Short Term Cardiovascular and Renal Effects of Moringa Oleifera Extracts and Stevia Rebaudiana Bertoni as add-on Therapy in a Population of Type II Diabetes Individuals
The aim of the study was the evaluation of cardiovascular and renal benefits of moringa oleifera and stevia rebaudiana Bertoni in patients with type 2 diabetes mellitus before and after 8 weeks of add-on therapy.
The investigators performed a non-randomized single-arm clinical trial with a before and
after design, carried out from November 2016 and May 2017.
Intervention consisted of the administration of a daily consummation of 425 ml of drink
containing the extracts of 1,38mg of leaves extracts of moringa oleifera and 23,46 mg of
stevia rebaudiana Bertoni leaves extracts lasting 45 days. Before and after intervention, the
following were done by the participants: bioelectrical impedance analysis (BIA), blood
pressure measurements, fasting blood sugar, HbA1c, lipid profiles, liver function tests,
kidney function tests, urinary excretion of albumin tests and full blood counts. These were
followed by morphological workup including Electrocardiograms (ECGs), transthoracic heart
ultrasounds and Ambulatory Blood Pressure Measurements (ABPM), also done before and after
intervention.
Clinical evaluation with fasting blood sugar control, blood pressure controls and urinary
excretion albumin tests were done for safety purposes.
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