Benefits of a Hibiscus Sabdariffa and Stevia Rebaudiana Drink in Patients With Type 2 Diabetes Mellitus Before and After 8 Weeks of add-on Therapy Clinical Trial
Official title:
Short Term Effects of a Hibiscus Sabdariffa and Stevia Rebaudiana Drink on Cardiac Relaxation and Urinary Albumin Excretion in a Group of Diabetic Type 2 Subjects
The aim of this study is to evaluate the effects of a Hibiscus Sabdariffa and Stevia Rebaudiana drink on cardiac relaxation and urinary albumin excretion in a group of diabetic type II patients.
The investigators performed a non-randomized single-arm clinical trial with a before and
after design, carried out from November 2016 and May 2017.
Intervention consisted of the administration of a Hibiscus-Stevia drink at a dose of 4 mg /
kg / day for Stevia and 4 g / day for Hibiscus for a period of 8 weeks. Before and after
intervention, the following were done by the participants: bioelectrical impedance analysis
(BIA), blood pressure measurements, fasting blood sugar, HbA1c, lipid profiles, liver
function tests, kidney function tests, urinary excretion of albumin tests and full blood
counts. These were followed by morphological workup including Electrocardiograms (ECGs),
transthoracic heart ultrasounds and Ambulatory Blood Pressure Measurements (ABPM), also done
before and after intervention.
Clinical evaluation with fasting blood sugar control, blood pressure controls and urinary
excretion albumin tests were done at the 30th and 60th days for safety purposes.
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