Osteoarthritis of Multiple Joints Clinical Trial
Official title:
Effects of Sulfur Water and Mud Therapy on Serotonin Activity and Biochemical Parameters in Patients' Osteoarthrosis
This study is to examine the effects of sulfur bath and mud therapy on serotonin levels and other biochemical parameters in the blood of the osteoarthritis patients, as well as water the application of exercise in water effects the results we receive.
Status | Recruiting |
Enrollment | 60 |
Est. completion date | September 1, 2020 |
Est. primary completion date | April 18, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 50 Years to 65 Years |
Eligibility |
Inclusion Criteria: 1. Ages of 50 - 65 , both sexes 2. Patients diagnosed with hip and / or knee OA without having used balneotherapy in the previous year 3. Patients who have not changed their medication in the last 2 months 4. Patients who have not received injections into the hip and / or knee joint in the last 6 months (PRP, Diprofos…) Exclusion Criteria: 1. Secondary hip and / or knee OA 2. Patients with MOA inhibitors, selective serotonin inhibitors, morphine, lithium and methyldopa in therapy 3. Visible disruption of hip and / or knee joint structures 4. Treatment of malignancy 5. Diseases of the heart, lungs, decompensated conditions of other organs, infections, active bleeding 6. Severe hip and / or knee joint injuries, fractures, and previous surgical procedures 7. Physical therapy, balneotherapy back one year |
Country | Name | City | State |
---|---|---|---|
Serbia | Specializd Rehabilitation Hospital Banja Koviljaca | Loznica | Banja Koviljaca |
Lead Sponsor | Collaborator |
---|---|
Specialized Rehabilitation Hospital Banja Koviljaca |
Serbia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The serotonin levels | Serotonin concentration | Time Frame: Baseline vs. 12-days | |
Secondary | Marker of inflammation | Sedimentation concentration | Time Frame: Baseline vs. 12-days | |
Secondary | Analysis of hemoglobin | Concentration of hemoglobin (g/L) | Time Frame: Baseline vs. 12-days | |
Secondary | Analysis of red blood cell counts | The total number of erythrocytes / L | Time Frame: Baseline vs. 12-days |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
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