Impact of Stent Length and Diameter on Patients Undergoing Primary PCI

ST-segment Elevation Myocardial Infarction (STEMI) Clinical Trial

Official title:

Impact of Stent Length and Diameter on Short Term Outcomes in Patients With ST Segment Elevation Myocardial Infarction Undergoing Primary PCI.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04110691
• Other study ID #: coronary stents
• Status: Not yet recruiting
• Start date: July 1, 2020
• Est. completion date: January 28, 2022

Study information

• Verified date: May 2020
• Source: Assiut University
• Contact: Doaa Ahmed Fouad, Professor
• Phone: 01001085828
• Email: fouaddoaa[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of the study is to evaluate the Impact of coronary stent length and/or diameter in patients with ST segment myocardial infarction undergoing primary PCI, on Short term clinical outcomes.

Description:

• ST segment elevation myocardial infarction is serious condition to the blood supply to the heart muscle. Rapid reperfusion of the ischemic myocardium using percutaneous coronary intervention (PCI) is the standard treatment for acute myocardial infarction (MI) to rescue the ischemic myocardium and reduce infarction size.

• There are two types of stents:

1. Drug-eluting stent which achieving local drug delivery to the injured blood vessel at the time of intervention, a drug is released from a polymer coating or loaded directly onto the stent (2). This is the best one.

2. Bare metal stent is the old one and not effective as DES in reducing vascular restenosis by suppressing smooth muscle cell (SMC) proliferation.

• The management of long coronary lesions by percutaneous coronary intervention (PCI) has become increasingly important because of the rising incidence of long or complex lesions in aging populations (3) Stent length has been considered as an important predictor of adverse events after PCI. The exact impact of lesion length on the short- and long-term clinical outcomes of DES implantations is not clear yet.

• Myocardial necrosis complicates one-third of percutaneous coronary intervention (PCI) and may adversely affect the outcome(4)

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 200
• Est. completion date: January 28, 2022
• Est. primary completion date: September 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients with ST segment myocardial infarction who are eligible for PCI.

• All categories (all age groups and both sex groups)

Exclusion Criteria:

• Patients with previous PCI.

• Patients of ectatic lesions.

• Patients with with multi vessel disease and suitable for CABG.

• Patients with complex lesions including bifurcational lesions and LM stenting.

Related Conditions & MeSH terms

• Infarction
• Myocardial Infarction
• ST Elevation Myocardial Infarction
• ST-segment Elevation Myocardial Infarction (STEMI)

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	prognosis of patients with ST segment myocardial infarction undergoing primary PCI	prognosis will be measured with ECG and ECHO	3 months