ST-segment Elevation Myocardial Infarction (STEMI) Clinical Trial
Official title:
Impact of Stent Length and Diameter on Short Term Outcomes in Patients With ST Segment Elevation Myocardial Infarction Undergoing Primary PCI.
The goal of the study is to evaluate the Impact of coronary stent length and/or diameter in patients with ST segment myocardial infarction undergoing primary PCI, on Short term clinical outcomes.
- ST segment elevation myocardial infarction is serious condition to the blood supply to
the heart muscle. Rapid reperfusion of the ischemic myocardium using percutaneous
coronary intervention (PCI) is the standard treatment for acute myocardial infarction
(MI) to rescue the ischemic myocardium and reduce infarction size.
- There are two types of stents:
1. Drug-eluting stent which achieving local drug delivery to the injured blood vessel
at the time of intervention, a drug is released from a polymer coating or loaded
directly onto the stent (2). This is the best one.
2. Bare metal stent is the old one and not effective as DES in reducing vascular
restenosis by suppressing smooth muscle cell (SMC) proliferation.
- The management of long coronary lesions by percutaneous coronary intervention (PCI) has
become increasingly important because of the rising incidence of long or complex lesions
in aging populations (3) Stent length has been considered as an important predictor of
adverse events after PCI. The exact impact of lesion length on the short- and long-term
clinical outcomes of DES implantations is not clear yet.
- Myocardial necrosis complicates one-third of percutaneous coronary intervention (PCI)
and may adversely affect the outcome(4)
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