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Clinical Trial Summary

Volume and Dose De-Intensified Radiotherapy for p16+ Squamous Cell Carcinoma of the Oropharynx: A Multi-Centre, Single Arm Prospective Cohort Study


Clinical Trial Description

De-intensified radiotherapy to a dose of 60 Gy to the primary tumour and involved lymph nodes and 54 Gy to subclinical regions at risk in 30 fractions. Omission of level IB lymph node regions from the elective nodal volumes. Chemotherapy will be administered as per standard of care, consisting of concurrent cisplatin (high-dose: 100mg/m2 IV every 3 weeks or low-dose: 40mg/m2 IV every week) or cetuximab (at the discretion of medical oncologist). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04104945
Study type Interventional
Source AHS Cancer Control Alberta
Contact Harvey Quon, MD
Phone 403-521-3619
Email harvey.quon@ahs.ca
Status Recruiting
Phase N/A
Start date January 12, 2021
Completion date October 21, 2028

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