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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04023214
Other study ID # STH15983
Secondary ID
Status Completed
Phase
First received
Last updated
Start date July 25, 2011
Est. completion date December 31, 2018

Study information

Verified date July 2019
Source Sheffield Teaching Hospitals NHS Foundation Trust
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This pilot study will compare endothelial function in patients with ADPKD with matched healthy volunteers and normotensive chronic kidney disease stage 1 & 2 patients. Patients will undergo a single assessment of endothelial function and measurement of plasma and urine levels of biomarkers of endothelial function.


Description:

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Study Design


Related Conditions & MeSH terms


Intervention

Diagnostic Test:
Peripheral (digital) arterial tonometry
This will be measured using the EndoPAT system (Itamar Medical)

Locations

Country Name City State
n/a

Sponsors (2)

Lead Sponsor Collaborator
Sheffield Teaching Hospitals NHS Foundation Trust University of Sheffield

Outcome

Type Measure Description Time frame Safety issue
Primary Reactive hyperemia index (RHI) EndoPAT values (Endoscore) Baseline
Secondary Systolic and diastolic Blood pressure mm Hg Baseline
Secondary Proteinuria Protein creatinine ratio Baseline
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