Nebulized Lidocaine to Prevent Cough at Emergence From Anesthesia

Cough, General Anesthesia, Extubation, Lidocaine, Sore Throat Clinical Trial

Official title:

Nebulized Lidocaine Versus Placebo to Prevent Cough at Emergence From Anesthesia: a Double Blind Prospective Randomised Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04000633
• Other study ID #: lidocaïne cough prevention
• Status: Recruiting
• Phase: N/A
• Start date: June 1, 2019
• Est. completion date: December 31, 2019

Study information

• Verified date: June 2019
• Source: Mongi Slim Hospital
• Contact: Mhamed Sami Mebazaa, professor
• Phone: 0021622252589
• Email: msmebazaa[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

our study aimed to evaluate the effect of nebulized lidocaine to decrease the incidence of cough and sore throat after extubation after surgeries requiring endotracheal intubation.

Description:

our study aimed to evaluate the effect of nebulized lidocaine to decrease the incidence of cough and sore throat after extubation after surgeries requiring endotracheal intubation.

This randomized controlled study will compare the effect of Lidocaine and placebo nebulization in the immediate pre operative period in order to evaluate the effectiveness in reducing post extubation cough and sore throat.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 80
• Est. completion date: December 31, 2019
• Est. primary completion date: December 31, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• age>18 years

• ASA status I or II

Exclusion Criteria:

• Unexpected difficult laryngoscopy

• Surgery>3 hours

Related Conditions & MeSH terms

• Cough
• Cough, General Anesthesia, Extubation, Lidocaine, Sore Throat
• Pharyngitis

Intervention

Drug:
• Lidocaine 2%
the patients of this group will recieve nebulization of 5 ml of 2% lidocaine prior to induction of general anesthesia
• Normal saline
Normal saline

Locations

Country	Name	City	State
Tunisia	Mongi Slim Hospital	La Marsa	Tunis

Sponsors (1)

Lead Sponsor	Collaborator
Mongi Slim Hospital

Country where clinical trial is conducted

Tunisia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	incidence of cough at emergence from general anesthesia	evaluation of incidence of cough at emergence from general anesthesia	30 minutes after the end of surgery
Secondary	incidence of sore throat	evaluation of incidence of sore throat	24 hours after tracheal extubation