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Vagus Nerve Stimulation in Treatment of Postural Orthostatic Tachycardia Syndrome — POTS  

Postural Orthostatic Tachycardia Syndrome Clinical Trial

Official title:
Vagus Nerve Stimulation in Treatment of Postural Orthostatic Tachycardia Syndrome

Clinical Trial Summary

Postural orthostatic tachycardia (POTS) is characterized by abnormalities in the autonomic nervous system in the body. The autonomic nervous system controls and regulates body functions such as heart rate, breathing, digestion, and more. The investigator has shown that patients with POTS have higher cardiovascular and adrenergic activating autoantibodies (AAb), which likely changes the normal make-up of POTS. There are autoantibodies that have been suggested by a few reports of their presence in POTS, but their role different aspects of POTS is unknown. The study will look at the body's responses in patients with POTS. The crossover study design is to have half of the patients will start with sham followed by active stimulation and half will start by active followed by sham stimulation. It is anticipated that results will provide a potential therapeutic approach based on the understanding of POTS.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03930914
Study type Interventional
Source University of Oklahoma
Contact
Status Completed
Phase N/A
Start date November 4, 2019
Completion date December 7, 2021
View Details
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