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BUCYE Conditioning Regimen for PCNSL Undergoing Auto-HSCT

Primary Central Nervous System Lymphoma Clinical Trial

Official title:
Busulfan+ Cyclophosphamide+ Etoposide Conditioning Regimen for Primary Central Nervous System Lymphoma Undergoing Autologous Hematopoietic Stem Cell Transplantation

Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy of BUCYE conditioning regimens in primary central nervous system lymphoma undergoing autologous hematopoietic stem cell transplantation.

Clinical Trial Description

The prognosis of patients with primary central nervous system lymphoma (PCNSL) is poor. Recent studies have demonstrated that autologous hematopoietic stem cell transplantation (auto-HSCT) could improve the prognosis of these patients. However, the optimal conditioning regimen of auto-HSCT remains unclear. In this study, the investigators evaluated the safety and efficacy of BUCYE conditioning regimens in PCNSL undergoing auto-HSCT. ;

Study Design

Related Conditions & MeSH terms

  • Autologous Hematopoietic Stem Cell Transplantation
  • Conditioning
  • Lymphoma
  • Primary Central Nervous System Lymphoma
Clinical Trial Details
NCT number NCT03733327
Study type Interventional
Source Nanfang Hospital of Southern Medical University
Contact Qifa Liu
Phone +862061641611
Email liuqifa628@163.com
Status Recruiting
Phase Phase 2/Phase 3
Start date November 2018
Completion date October 2021
View Details
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