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Esophageal Balloon Calibration in Assisted Ventilation Mode — EBC-PSV+Sigh  

Respiratory Failure Clinical Trial

Official title:
Esophageal Balloon Calibration During Assisted Ventilation Modes and Sigh: a Feasibility Study

Clinical Trial Summary

Esophageal balloon calibration (EBC) has been proposed during controlled mechanical ventilation in intubated patients in order to optimize esophageal pressure (Pes) signal. Actually, at our knowledge, no data exist about EBC during assisted ventilatory modes such as Pressure Support Ventilation (PSV). The primary endpoint of the present investigation is to assess the feasibility of EBC during PSV and PSV plus Sigh.

Clinical Trial Description

Assisted ventilatory modes, nowadays, have been proved to reduce complications related to controlled mechanical ventilation. With these modes, ventilatory cycling is under the patient's control to an extent depending on the type of ventilatory modality.

Sigh improves oxygenation and lung mechanics during pressure control ventilation and pressure support ventilation (PSV) in patients with acute respiratory distress syndrome.

In order to better quantify the effects of both PSV and PSV plus Sigh on respiratory mechanics, the esophageal pressure monitoring could be helpful. However, esophageal pressure (Pes) assessment requires esophageal ballon calibration (EBC) as demonstrated in intubated patients under controlled mechanical ventilation.

At our knowledge, no data exist about EBC during assisted ventilatory modes. The primary aim of the present study is to evaluate the effects of PSV and PSV plus Sigh ventilation on esophageal balloon best volume in patients admitted to the intensive care unit for acute respiratory failure.

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Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03721237
Study type Interventional
Source Azienda Ospedaliero Universitaria Maggiore della Carita
Contact
Status Completed
Phase N/A
Start date November 15, 2018
Completion date August 1, 2019
View Details
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