Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia

Postoperative Pain After Knee Arthroscopy Clinical Trial

Official title:

Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia After Arthroscopic Anterior Cruciate Ligament Reconstruction (ACL)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03530280
• Other study ID #: pregabalin
• Status: Completed
• Phase: N/A
• Start date: June 1, 2018
• Est. completion date: December 1, 2018

Study information

• Verified date: October 2019
• Source: Ankara Diskapi Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.

Description:

Patients who American Society of Anesthesiologists (ASA) classification I to II scheduled to undergo arthroscopically assisted ACL reconstructions under spinal anesthesia are included in this study. The first group is administered 150 mg oral pregabalin 1 hour before surgery and the postoperative sham block was performed with an ultrasound probe. The second group is the control group; patients in this group are administered a placebo capsule 1 hour before surgery and sham block was performed with an ultrasound probe.The third group is administered a placebo capsule 1 hour before surgery and postoperative adductor canal block is performed. All patients will be received postoperative a tramadol i.v. patient control analgesia device. At the end of 24 hours, the total amount of tramadol consumed by the patient will be recorded from the patient control analgesia. NRS score, white fast track, satisfaction will be questioned.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 51
• Est. completion date: December 1, 2018
• Est. primary completion date: October 1, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Patients between the ages of 18 and 70 years

• American Society of Anesthesiologists I or II

• Scheduled to undergo knee arthroscopy

Exclusion Criteria:

• allergic to any medicines

• History of drug or alcohol abuse,

• Opioids or sedative medications

• History of psychiatric conditions

• Pregnant or lactating women

Related Conditions & MeSH terms

• Pain, Postoperative
• Postoperative Pain After Knee Arthroscopy

Intervention

Drug:
• pregabalin (lyrica)
preoperative pregabalin and the postoperative sham block will perform.
• Placebo oral tablet
The preoperative placebo oral tablet and the postoperative sham block will perform.
• adductor canal block including bupivacaine
The preoperative placebo oral tablet and adductor channel block including 10 mL of 0.25% bupivacaine with 5 µg/mL epinephrine

Locations

Country	Name	City	State
Turkey	Diskapi Teaching and Research Hospital	Ankara	Altindag

Sponsors (1)

Lead Sponsor	Collaborator
Ankara Diskapi Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	11-point numerical rating scale (NRS)	11-point numerical rating scale for pain (0='no pain' and 10='worst pain possible pain') were explained.	24 hours
Primary	tramadol consumption	24 hours tramadol consumption will be recorded as milligrams	24 hours