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Clinical Trial Summary

This study aims to compare two different protocols commonly used in the management of post thyroidectomy hypoparathyroidism : PTH based calcium repletion and empiric repletion. The investigators aim to compare the quality of life associated with these two protocols in a randomized trial.


Clinical Trial Description

Enrolled patients will be randomized in two treatment groups. In group 1, all patients will receive calcium carbonate and calcitriol in the post-operative period, with standardized weaning. In group 2, patients will be prescribed calcium carbonate and calcitriol only if their post-operative PTH dosage is 25% or less of the pre-operative dosage, or if post-operative PTH is inferior to 15. The Short-Form 36 (SF-36) questionnaire (French canadian version) will be used to assess quality of life pre-operatively and at post-op week 1 and 4. Symptoms of hypocalcemia and adverse effects of calcium carbonate and calcitriol will be monitored at week 1 and 4. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03249012
Study type Interventional
Source CHU de Quebec-Universite Laval
Contact Jean-Philippe Vezina, MD, FRCSC
Phone 418-649-0252
Email jean-philippe.vezina@fmed.ulaval.ca
Status Recruiting
Phase N/A
Start date September 1, 2017
Completion date September 1, 2025

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