Different Chemotherapy Protocols Combined With Intensity Modulated Radiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

Drug-Related Side Effects and Adverse Reactions Clinical Trial

Official title:

the General Hospital of PLA

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03177174
• Other study ID #: S2017-030-02
• Status: Completed
• Phase: N/A
• Start date: June 12, 2017
• Est. completion date: February 1, 2020

Study information

• Verified date: February 2020
• Source: Chinese PLA General Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study was to evaluate the efficacy ,toxic reaction and safety of different chemotherapy combined with radiotherapy on patients with locally advanced nasopharyngeal carcinoma.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 150
• Est. completion date: February 1, 2020
• Est. primary completion date: January 1, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Patients > 18, <70 years old, with locally advanced nasopharyngeal carcinoma.

Exclusion Criteria:

• patients who had accepted radiotherapy before patients with any ather types of cancer

Related Conditions & MeSH terms

• Drug-Related Side Effects and Adverse Reactions
• Nasopharyngeal Carcinoma

Intervention

Drug:
• Cisplatin
radiotherapy combined with Chemotherapy Drugs, Cancer
• Docetaxel
Docetaxel

Locations

Country	Name	City	State
China	Chinese PLA general hospital	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Luo yanrong

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	changes in toxic reaction	incidence rate of the toxic reaction between three groups	5 years
Secondary	over survival	differences of over survival rate between three groups	5 years