Predictors of Occult Atrial Fibrillation in 171 Patients With Cryptogenic TIA and Minor Stroke

Cryptogenic Transient Ischemic Attack and Minor Stroke Clinical Trial

— HOLTER-21J  

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03166969
• Other study ID #: P14/08_HOLTER 21J
• Status: Completed
• Phase: N/A
• First received: September 12, 2016
• Last updated: May 23, 2017
• Start date: February 2007
• Est. completion date: January 2013

Study information

• Verified date: May 2017
• Source: Versailles Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Retrospective study, single-center, on 171 patients, presented a cryptogenic TIA and Minor stroke.

This study objective is to determine profitability of Holter 21 days for screening paroxystic ACFA / flutter in cryptogenic TIA/Minor stroke, and identify the predictive factors of discovery a paroxystic ACFA on Holter 21 days. Clinical and échocardiographics factors, and brain imaging (scanner and MRI) will be analyzed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 171
• Est. completion date: January 2013
• Est. primary completion date: January 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Cryptogenic TIA/Minor stroke

• Age > 18 years

• Medical care in Neuro Vascular Unit of CH Versailles

• Holter 21 days performed

Exclusion Criteria:

1. ACFA history

2. ECG or telemetry who showed ACFA before the Holter initializing

3. Carotid Stenosis / symptomatic vertebral

4. Arterial dissection

5. Prothrombotic state demonstrated by laboratory tests

6. Infective endocarditis

Related Conditions & MeSH terms

• Cryptogenic Transient Ischemic Attack and Minor Stroke
• Ischemic Attack, Transient
• Stroke

Intervention

Procedure:
• Holter 21 days

Locations

Country	Name	City	State
France	Centre Hospitalier de Versailles	Le Chesnay

Sponsors (1)

Lead Sponsor	Collaborator
Versailles Hospital

Country where clinical trial is conducted

France, 

References & Publications (1)

Sudacevschi V, Bertrand C, Chadenat ML, Tarnaud C, Pico F. Predictors of Occult Atrial Fibrillation in One Hundred Seventy-One Patients with Cryptogenic Transient Ischemic Attack and Minor Stroke. J Stroke Cerebrovasc Dis. 2016 Nov;25(11):2673-2677. doi: — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of atrial fibrillation detected on long duration ( 21 days) cardiac rythm holter monitoring	Atrial fibrillation >= 30 secondes	Day 21