A Dye for the Detection of Cancer of the Tongue and Mouth

Oral Squamous Cell Carcinoma (OSCC) Clinical Trial

Official title: A Phase I/II Study of the Fluorescent PARP1 Binding Imaging Agent PARPi-FL in Patients With Oral Squamous Cell Carcinomas

Status Recruiting

Clinical Trial Summary

The purpose of this study is to test if an investigational dye, called PARPi-FL, can be used to detect this type of cancer. This will be the first time that PARPi-FL is being tried in people. First, the investigators will test the safety of PARPi-FL at different doses to find out what effects, if any, it has on people. The investigators will also see which amount of PARPi-FL is best suited to detect cancers of the mouth and tongue.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Carcinoma
• Carcinoma, Squamous Cell
• Oral Squamous Cell Carcinoma (OSCC)
• Squamous Cell Carcinoma of Head and Neck

• NCT number: NCT03085147
• Study type: Interventional
• Source: Memorial Sloan Kettering Cancer Center
• Contact: Heiko Schoder, MD
• Phone: 212-639-2079
• Email: schoderh@mskcc.org
• Status: Recruiting
• Phase: Phase 1/Phase 2
• Start date: March 15, 2017
• Completion date: July 2026