Long-term Hemodialysis Catheter Removal and Delayed Replacement, Versus Exchange Over a Guidewire to Treat Catheter Related Blood Stream Infection

Catheter Related Blood Stream Infection Clinical Trial

Official title:

Prospective, Randomized Study of Long-term Hemodialysis Catheter Removal, Versus Guidewire Exchange to Treat Catheter Related Blood Stream Infection

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03054714
• Other study ID #: tunneled hemodialysis
• Status: Completed
• Phase: N/A
• First received: February 10, 2017
• Last updated: February 21, 2017
• Start date: November 1, 2011
• Est. completion date: November 30, 2016

Study information

• Verified date: February 2017
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Prospective, randomized Study of tunneled cuffed hemodialysis catheter removal and delayed replacement, versus exchange over a guidewire to treat catheter related blood stream infection

Description:

The aim of this study was to compare the clinical outcomes of catheter-related (CRBSI) managed with two different strategies: Guidewire exchange of the infected catheter with a new one over a guidewire versus catheter removal with delayed replacement.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 798
• Est. completion date: November 30, 2016
• Est. primary completion date: November 30, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 14 Years to 90 Years

Eligibility

Inclusion Criteria:

• All patients end stage renal disease on hemodialysis from tunneled cuffed dialysis catheters with suspected catheter-related bloodstream infection with no identifiable infection source except the catheter were included.

Exclusion Criteria:

• metastatic infection,

Related Conditions & MeSH terms

• Catheter Related Blood Stream Infection
• Communicable Diseases
• Infection

Intervention

Device:
• catheter replacement
catheter removal and delayed replacement, versus exchange over a guidewire

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	infection free survival		45 days