Oral Cavity Squamous Cell Carcinoma Clinical Trial
Official title:
Predictability of Carcinomatous Invasion of the Maxilla or Mandible: An Assessment of Radiologic Modalities With Histologic Correlation
This clinical trial studies how well helical computed tomography (CT), positron emission tomography (PET)/CT, magnetic resonance imaging (MRI), and cone beam computed tomography (CBCT) work alone or in combination in predicting whether tumor cells have spread to the jaw bone (jaw invasion) in patients with oral cancer. Imaging, such as helical CT, PET/CT, MRI, and CBCT, may help find out how far cancer has spread. Accurate prediction of the presence or absence of jaw invasion may help create a better surgical treatment plan for patients with oral cancer.
PRIMARY OBJECTIVES:
I. To determine which imaging modality or combination of imaging methods, in conjunction with
clinical and histological examination, will most accurately predict the presence or absence
of invasion of the mandible or maxilla by intraoral squamous cell carcinoma (SCC).
SECONDARY OBJECTIVES:
I. To compare the histopathologic findings to the radiologic findings.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03650699 -
Biofeedback Rehabilitation to Improve Speaking and Eating in Public
|
N/A | |
Recruiting |
NCT05098119 -
Neoadjuvant Sintilimab Combined With Reduction of Cycles of Chemotherapy in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma (OOC-002)
|
Phase 2 | |
Recruiting |
NCT05876247 -
Articulatory Adaptation Following Oral Cancer Treatment
|
||
Completed |
NCT03618654 -
Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma
|
Early Phase 1 | |
Recruiting |
NCT04801472 -
Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM)
|
N/A | |
Recruiting |
NCT04858269 -
First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients
|
Phase 2 | |
Active, not recruiting |
NCT03529604 -
Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients
|
||
Completed |
NCT03028766 -
WEE1 Inhibitor With Cisplatin and Radiotherapy: A Trial in Head and Neck Cancer
|
Phase 1 | |
Recruiting |
NCT05681039 -
Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).
|
Phase 2 | |
Completed |
NCT03510390 -
Metformin in Head and Neck Squamous Cell Carcinoma: Effect on Tissue Oxygenation
|
N/A | |
Recruiting |
NCT05578170 -
Efficacy and Safety of Neoadjuvant Pembrolizumab in III-IVA Resectable Oral Squamous Cell Carcinoma
|
||
Recruiting |
NCT05950737 -
Sentinel Node Biopsy in Early Oral Cancers a Tertiary Cancer Centre Experience
|
N/A | |
Recruiting |
NCT04333537 -
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
|
Phase 2/Phase 3 | |
Recruiting |
NCT03727594 -
Radioguided Selective Neck Dissection for Staging and Treatment of Oral Cavity and Oropharyngeal Squamous Cell Carcinoma
|
||
Terminated |
NCT02582008 -
Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy
|
Early Phase 1 | |
Recruiting |
NCT05749042 -
A Study of Concurrent Chemoradiotherapy Based of Cisplatin With or Without Sintilimab as First-line Therapy for Patients With Advanced Oral Cavity Squamous Cell Carcinoma
|
Phase 2 | |
Recruiting |
NCT06097468 -
Nisin in Oral Cavity Squamous Cell Carcinoma (OCSCC)
|
Phase 1/Phase 2 | |
Withdrawn |
NCT04892875 -
A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers
|
Phase 1 | |
Active, not recruiting |
NCT03784066 -
Durvalumab With or Without Tremelimumab in Resectable Locally Advanced Squamous Cell Carcinoma of the Oral Cavity
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT03381183 -
IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma
|
Phase 1 |