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The Effect of HMG-CoA Reductase Inhibition on Postprandial GLP-1 Secretion

Diabetes Mellitus, Type 2 Clinical Trial

Official title:
The Effect of HMG-CoA Reductase Inhibition on Postprandial GLP-1 Secretion

Clinical Trial Summary

The primary objective of the present study is to evaluate the effect of HMG-CoA reductase inhibition during 14 days on the postprandial plasma GLP-1 response in healthy individuals. Secondary objectives include the evaluation of HMG-CoA reductase inhibition on postprandial glucose tolerance, gallbladder emptying, gastric emptying, plasma responses of lipids, bile acids and pancreatic and enteric hormones known to influence glucose metabolism and appetite, and faecal content of bile acids and gut microbiota composition.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03018444
Study type Interventional
Source University Hospital, Gentofte, Copenhagen
Contact
Status Completed
Phase N/A
Start date October 2016
Completion date January 2017
View Details
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