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Clinical Trial Summary

Vascular cognitive impairment no dementia (VCIND) is very common among the aged and tends to progress to dementia, but there have been no proper large-scale intervention trials dedicated to it. VCIND caused by subcortical ischemic small vessel disease (hereinafter, subcortical VCIND) represents a relatively homogeneous disease process and is a suitable target for therapeutic trials investigating VCIND. Preclinical trials showed that Butylphthalide Soft Capsules is effective for cognitive impairment of vascular origin. In this randomized, double-blind, placebo-controlled trial, the investigators apply fMRI study the effects of Butylphthalide Soft Capsules in patients with VCIND.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02993367
Study type Interventional
Source The Second Hospital of Hebei Medical University
Contact Yifei Zhu, M.D.
Phone +8613303046666
Email [email protected]
Status Recruiting
Phase Phase 2/Phase 3
Start date January 2017
Completion date July 2019

See also
  Status Clinical Trial Phase
Completed NCT02640716 - Cog-VACCINE: Cognitive Training in Patients With Vascular Cognitive Impairment, no Dementia N/A
Recruiting NCT03306979 - Memory and Antioxidants in Vascular Impairment Trial Phase 2