Gestational Diabetes Clinical Trial
Official title:
Effect of Hyperemesis Gravidarum on 75 Gram Oral Glucose Tolerance Test Screening and Gestational Diabetes Mellitus
Hyperemesis gravidarum (HEG) is not only nausea and vomiting of pregnancy, but it is also a clinical syndrome including endocrine and metabolic complications. Recently, some investigators have been begun performing researches related to the development of gestational diabetes mellitus (GDM) in pregnant women with HEG because they think about those metabolic and endocrine complications of HEG.In the literature there are few studies assessing how HEG has effects on GDM or 75 gram oral glucose tolerance test (OGTT). So the investigators aim to evaluate the effects of HEG on 75 gram OGTT.
This retrospective controlled study conducted by Obstetrics and Gynecology clinics of
Kayseri Training and Research Hospital.Pregnant women who delivered at the Kayseri Education
and Training Hospital of Medicine, in Turkey, between January 2010 and September 2016 were
identified.This study was carried out with two groups. The study group consisted of women
hospitalized for Hyperemesis gravidarum (HEG) during first trimester of their pregnancy,
whereas the control group included all other women who delivered in the same
period.Screening for GDM was performed twice during pregnancy. The first screening was
performed during the first trimester using the random plasma glucose test with a cutoff
value of 109 mg/dl. Screening for GDM was performed for all women during their first
prenatal visit, regardless of the presence or absence of hyperemesis-associated symptoms.The
second screening was performed during the second trimester, between 24 and 27 weeks, using a
75-g oral glucose tolerance test (OGTT), after pregnant women with HEG got rid of
hyperemesis. GDM was diagnosed on the basis of the universal criteria established by the
International Association of Diabetes and Pregnancy Study Group: a plasma glucose level that
met or exceeded the fasting cutoff value 92 mg/dl, the first-hour cutoff value 180 mg/dl, or
the second-hour cutoff value 153mg/dl.
To be considered for diagnosis of pre-gestational diabetes mellitus, women had to meet at
least one of the following criteria: the fasting plasma glucose test with a cutoff value of
126 mg/dl or the random plasma glucose test with a cutoff value of 200 mg/dl or the
second-hour cutoff value 153mg/dl after 75 gram OGGT (American Diabetes Association) The
delivery midwifery and medical records were retrospectively evaluated. All of the patient's
body mass index (BMI,calculated as weight in kilograms divided by the square of height in
meters), urine ketone levels and ages were recorded separately both in the initial exam and
during performing 75 gram OGTT.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05081037 -
Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)
|
N/A | |
Active, not recruiting |
NCT03249896 -
Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes
|
N/A | |
Terminated |
NCT03749889 -
Low Carb vs Normal Carb in Pregnancy
|
N/A | |
Completed |
NCT03859193 -
Education Nutritional Video for Gestational Diabetics
|
N/A | |
Recruiting |
NCT05037526 -
Utility of Real Time Continuous Glucose Monitoring in the Care of Gestational Diabetes Versus Standard Care in Pregnancy Outcomes
|
N/A | |
Completed |
NCT06178250 -
Placenta, Fetal Liver, Sectional Ductus Venosus Volumes Examined by Three-dimensional Ultrasound in the Second Trimester
|
N/A | |
Not yet recruiting |
NCT06310356 -
Continuous Glucose Monitoring for Women With Gestational Diabetes
|
N/A | |
Not yet recruiting |
NCT06445530 -
Nutrition Optimization and Community Upliftment for Postpartum Recovery
|
N/A | |
Recruiting |
NCT02590016 -
Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial
|
Phase 4 | |
Not yet recruiting |
NCT00883259 -
Metformin and Gestational Diabetes in High-risk Patients: a RCTs
|
Phase 4 | |
Withdrawn |
NCT01947699 -
Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide
|
Phase 4 | |
Recruiting |
NCT03008824 -
Micronutrients in Pregnancy as a Risk Factor for Diabetes and Effects on Mother and Baby
|
N/A | |
Active, not recruiting |
NCT01340924 -
Relationship Between Gestational Diabetes and Type 2 Diabetes
|
||
Completed |
NCT00534105 -
Lipid Metabolism in Gestational Diabetes
|
N/A | |
Recruiting |
NCT00371306 -
Comparison of Glucovance to Insulin for Diabetes During Pregnancy
|
N/A | |
Completed |
NCT03388723 -
Intergenerational Programming of Diabesity in Offspring of Women With Gestational Diabetes Mellitus
|
||
Recruiting |
NCT04521712 -
Postpartum Glycemia in Women at Risk For Persistent Hyperglycemia
|
N/A | |
Enrolling by invitation |
NCT03307486 -
Gestational Diabetes: a Cohort Study
|
N/A | |
Active, not recruiting |
NCT03301792 -
Group Versus Traditional Prenatal Care for Diabetes
|
N/A | |
Enrolling by invitation |
NCT05603793 -
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
|