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Immunophenotyping of Patients With Postoperative SIRS

Systemic Inflammatory Response Syndrome Clinical Trial

Official title:
Immunophenotyping of Patients Undergoing Open Heart Surgery to Assess Their Susceptibility of Developing a Systemic Inflammatory Response Syndrome (SIRS)

Clinical Trial Summary

The purpose of this study is to develop an immune-phenotype based prediction of postoperative SIRS in patients undergoing open heart surgery.

Clinical Trial Description

The study will have a pre-, intra and postoperative phase in which several demographic and clinical variables will be assessed. The samples for the immunophenotypic analysis will be drawn directly after induction of anesthesia and at various time points after end of surgery. The diagnosis of SIRS will be made during routine clinical visits on the first seven postoperative days using the Sepsis-related Organ Failure Assessment score (SOFA-score). The patients will be followed up for 30 days. ;

Study Design

Related Conditions & MeSH terms

  • Syndrome
  • Systemic Inflammatory Response Syndrome
Clinical Trial Details
NCT number NCT02957175
Study type Observational
Source University of Bonn
Contact Christian Bode, MD
Phone +4922828714119
Email christian.bode@ukb.uni-bonn.de
Status Recruiting
Phase
Start date November 2016
Completion date May 2021
View Details
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