Quantitative Cardiac Parametric Mapping

Cardiomyopathy, Myocarditis, Ischemic Heart Disease Clinical Trial

— Myomapping  

Official title:

Novel Magnetic Resonance Imaging Techniques for Quantitative Cardiac Parametric Mapping

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02855554
• Other study ID #: Pro00035552
• Status: Recruiting
• Phase: N/A
• Start date: June 20, 2014
• Est. completion date: October 15, 2024

Study information

• Verified date: November 2023
• Source: Medical University of South Carolina
• Contact: Mark Ghent, BA
• Phone: 843-876-7148
• Email: ghent[@]musc.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 240
• Est. completion date: October 15, 2024
• Est. primary completion date: October 15, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Subject must be 18-90 years of age.

• Subject must be previously diagnosed with or suspected to have one of the following conditions.

• Myocardial ischemia or infarction (group 1)

• Hypertrophic cardiomyopathy (group 2)

• Infiltrative cardiomyopathy (group 3)

• Myocarditis (group 4)

• Subject must have been referred for a clinically indicated CMR.

Exclusion Criteria:

• Subject has any implanted device or condition in which an MR scan would be contraindicated.

• Subject has an acute psychiatric disorder or is cognitively impaired.

• Subject is using or is dependent on substances of abuse.

• Subject is unwilling to comply with the requirements of the protocol.

• Subject has previously entered this study.

• Subject has an allergy against MRI contrast agents.

• Subject is in acute unstable condition.

Related Conditions & MeSH terms

• Cardiomyopathies
• Cardiomyopathy, Myocarditis, Ischemic Heart Disease
• Coronary Artery Disease
• Heart Diseases
• Myocardial Ischemia
• Myocarditis

Intervention

Other:
• Cardiac Magnetic Resonance (CMR) imaging techniques
Evaluation of clinical potential of fast quantitative myocardial tissue characterization using recently emerged CMRI techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases.

Locations

Country	Name	City	State
United States	Medical University of South Carolina	Charleston	South Carolina

Sponsors (1)

Lead Sponsor	Collaborator
Medical University of South Carolina

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.		2 years