Peak Systolic Global Longitudinal Strain and Low Cardiac Output Syndrome After Cardiac Surgery

Low Cardiac Output Syndrome After Adult Cardiac Surgery Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02771080
• Other study ID #: CHULgstrain
• Status: Completed
• Phase: N/A
• First received: May 11, 2016
• Last updated: November 22, 2016
• Start date: June 2016
• Est. completion date: September 2016

Study information

• Verified date: June 2016
• Source: University Hospital of Liege
• Contact: n/a
• Is FDA regulated: No
• Health authority: Belgium: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This is a retrospective observational study to assess the relationship between peak systolic global longitudinal strain measured on pre-cardiopulmonary bypass trans-esophageal echo images predicts post-operative low cardiac output syndrome defined as the need for an inotropic support during 24 hours or longer.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 275
• Est. completion date: September 2016
• Est. primary completion date: September 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Cardiac surgery involving the use of cardiopulmonary bypass

• Availability of pre-cardiopulmonary bypass trans-oesophageal echo images allowing measurement of the peak systolic global longitudinal strain

Exclusion Criteria:

• Preoperative atrial fibrillation

• Preoperative critical state

• Emergent/salvage surgery

• Heart transplant surgery

• Left ventricular assist device implantation

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Cardiac Output, Low
• Low Cardiac Output Syndrome After Adult Cardiac Surgery
• Syndrome

Intervention

Procedure:
• Cardiac surgery

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital of Liege

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Post-operative low cardiac output syndrome	Need for pharmacological inotropic support during 24 hours or more post-operatively	30 days	No
Secondary	Length of intensive care unit stay		30 days	No
Secondary	Length of hospital stay		30 days	No
Secondary	30-day or in hospital mortality		30 days	No
Secondary	duration of post-operative mechanical ventilation		30 days	No
Secondary	post-operative acute kidney injury		30 days	No
Secondary	Need for readmission to the intensive care		30 days	No