ST Elevation Myocardial Infarction Clinical Trial
Official title:
A Phase II Randomised, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety and Tolerability of Oral NP202 in Adults Who Have Left Ventricular Systolic Dysfunction Following Myocardial Infarction
NP202 is an experimental drug being developed by Armaron Bio Pty Ltd for potential use as a treatment for people after they have had a heart attack (MI).
After someone has a MI, their heart 'remodels', which means that it changes in size and
shape. This damage can lead to it being weaker and less efficient, and ultimately to major
heart problems. There are some drugs currently available which help prevent remodelling and
are used for treatment post-MI. However, there is still a high rate of remodelling and major
heart problems in people post-MI. NP202 works in a different way to the drugs that are
currently approved, and has been shown in animal studies to prevent post-MI remodelling.
This study will assess NP202 versus placebo on remodelling over a 3 month treatment period,
with 1 month follow up
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