Clinical Trials Logo
  1. Home
  2. Other
  3. NCT02385266

Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain — UCPPS  

Chronic Prostatitis With Chronic Pelvic Pain Syndrome Clinical Trial

Official title:
Brain Imaging-based Strategies for Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy of D-Cycloserine versus placebo treatment in reducing pain from urological chronic pelvic pain syndrome (UCPPS).

Clinical Trial Description

This is a double blinded, randomized control trial (RCT) over a 21 week period that aims to evaluate the treatment efficacy of placebo and D-cycloserine(DCS) in men suffering from UCPPS. The brain functional and anatomical properties associated with treatment response will also be examined. This study will emphasize on comparing, both clinically and by brain imaging, the analgesic response to placebo in both placebo responders and non-responders in addition to a novel treatment (DCS) that targets the brain's pain mechanism for UCPPS. Subjects will be randomized to 2 arms, in a 1:1 ratio, to a DCS medication group (n=20) and a placebo medication group (n=20). Questionnaire outcomes and brain scans will occur prior to initiating treatment and at the end of the treatment period. The actual visits required are minimized, 9 visits spread out over 21 weeks, as pain, quality of life and pill ingestion timings are collected using a secure study website accessible electronically. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02385266
Study type Interventional
Source Northwestern University
Contact
Status Terminated
Phase Phase 4
Start date September 2013
Completion date June 2016
View Details
See also
  Status Clinical Trial Phase
Completed NCT04552431 - Chronic Prostatitis Collaborative Research Network Clinical Trial- Ciprofloxacin and Tamsulosin Phase 2
Not yet recruiting NCT05366517 - Repeating LiST for Refractory Non-bacterial Prostatitis/Pelvic Pain Syndrome N/A
Completed NCT00672087 - Diagnostic Challenges in IC (and Male CPPS)
Completed NCT03213938 - Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome N/A
Recruiting NCT00775515 - Laparoscopic Prostatectomy for Chronic Prostatitis Phase 2
Completed NCT01676857 - Chemokine Mechanisms in Chronic Pelvic Pain
Completed NCT00826514 - An Efficacy And Safety Study Of Tanezumab For The Treatment Of Pain Associated With Chronic Abacterial Prostatitis Phase 2
Completed NCT06064448 - Clinical Observation of Ningmitai Capsule in Treating Chronic Pelvic Pain Syndrome With Erectile Dysfunction Phase 4
Completed NCT04446598 - Management of Prostatodynia in Younger Patients With Non-ablative Erbium:YAG Intraurethral Laser N/A
Completed NCT00701311 - An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome Phase 2
Completed NCT04275297 - Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain Syndrome N/A
Active, not recruiting NCT05075551 - Analyzing the Brain Alterations of Acupuncture on Patients With CP/CPPS Evaluated by fMRI N/A
Completed NCT06016595 - Chronic Prostatitis/Chronic Pelvic Pain Syndrome Patients
Active, not recruiting NCT01828996 - Shocking Therapy for Chronic Pelvic Pain Syndrome N/A
Recruiting NCT03629769 - Effects of Proxelan Somministration in Patients With Chronic Prostatitis Phase 3
Recruiting NCT06345014 - The Efficacy and Safety of OM-89 in Patients With Recurrent Chronic Prostatitis/Chronic Pelvic Pain Syndrome Phase 4
Recruiting NCT06115083 - Effects of Pelvic Floor Training in Male Chronic Pelvic Pain, Correlation Between Subjective and Objective Outcomes N/A
Completed NCT03167216 - Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction Early Phase 1
Terminated NCT00464373 - Botulinum Toxin Type A for the Treatment of Male Chronic Pelvic Pain Syndrome Phase 3
Not yet recruiting NCT06299683 - Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment N/A