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Imaging and Understanding BOS in Lung Transplantation

Bronchiolitis Obliterans Syndrome Clinical Trial

Official title:
Imaging and Understanding BOS in Lung Transplantation

Clinical Trial Summary

This study is a prospective, non-randomized, longitudinal, observational study that will recruit about 5 lung transplant patients per year for 3 years.

Clinical Trial Description

This study is a prospective, non-randomized, longitudinal, observational study that will recruit about 5 lung transplant patients per year for 3 years. We will follow these patients at 6 months and 1 year with Hyperpolarized Helium-3 Magnetic Resonance Imaging and image guided bronchial biopsies to detect early BOS and to better understand BO disease progression. The biopsies will provide future research for rapid determination of cellular and molecular mechanisms that lead to BOS and to facilitate identification and validation of translatable pharmaceutical targets. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02316392
Study type Observational
Source Children's Hospital Medical Center, Cincinnati
Contact
Status Completed
Phase
Start date December 2014
Completion date February 2017
View Details
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