Clinical Trials Logo

Clinical Trial Summary

A high platelet reactivity in patients with severe symptomatic Aortic Stenosis (AS) selected for TAVI (Transcatheter aortic valve implantation) procedure has been demonstrated previously, and the use of double antiaggregation therapy (DAPT) with Clopidogrel and Acetylsalicylic acid (ASA) do not achieve consistent and adequate suppression of platelet reactivity. The purpose of this study is evaluate the efficacy of ticagrelor alone versus DAPT with clopidogrel and aspirin for the suppression of high platelet reactivity following TAVI.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02224066
Study type Interventional
Source Hospital de Meixoeiro
Contact
Status Completed
Phase Phase 4
Start date January 2016
Completion date August 2018

See also
  Status Clinical Trial Phase
Recruiting NCT05465655 - Cara CDRM (Conduction Disturbance Risk Monitor) 2.0 N/A
Recruiting NCT04870424 - Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement Phase 3
Completed NCT02758964 - Evaluation of Cerebral Thrombembolism After TAVR
Recruiting NCT05758701 - CT TAVR Abdomen Study Phase 4
Active, not recruiting NCT04281771 - Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI N/A
Enrolling by invitation NCT06212050 - Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic Stenosis
Recruiting NCT04573049 - The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement Phase 4
Recruiting NCT05235555 - EffecTAVI Registry
Completed NCT05082337 - The SAVVY Guidewire in Transcatheter Aortic Valve Replacement Procedures N/A
Completed NCT01627691 - REPRISE II: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus™ Valve System N/A
Recruiting NCT05075590 - Coronary Access After Supra-Annular THV Implantation N/A
Completed NCT01651780 - Open-label, Randomized Trial in Patients Undergoing TAVR to Determine Safety & Efficacy of Bivalirudin vs UFH Phase 3
Recruiting NCT05259241 - ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI) N/A
Completed NCT04489914 - Observational Study on the Application of High-Flow Therapy After Percutaneous Transfemoral Aortic Valve Replacement
Recruiting NCT03649594 - Risk Stratification Post TAVI Using TEG
Completed NCT04659538 - The CAPTIS® Study - Embolic Protection in TAVR N/A
Recruiting NCT04107038 - Monitored Anesthesia Care vs. General Anesthesia for Transcatheter Aortic Valve Replacement N/A
Withdrawn NCT04268160 - GPx Activity in Subjects With Aortic Stenosis Undergoing TAVR
Recruiting NCT02812953 - Biological Collection and Registry of Patients Who Will Have a TAVR (Transcatheter Aortic Valve Replacement) Intervention
Recruiting NCT05217888 - The Sentinel Registry