Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to compare the therapeutic strategies of rate control versus rhythm control in cardiac surgery patients who develop in-hospital postoperative atrial fibrillation or atrial flutter (AF). In patients who develop AF during hospitalization after cardiac surgery, the hypothesis is that a strategy of rhythm control will reduce days in hospital within 60 days of the occurrence of AF compared to a strategy of rate control.


Clinical Trial Description

The purpose of the research is to compare two strategies for treating atrial fibrillation or atrial flutter, both of which are referred to as AF, after cardiac surgery. AF is the most common complication after cardiac surgery. AF is when the upper chambers of the heart (atria) experience disorganized electrical activity which causes the heart beat to be irregular. The two treatment strategies to be used in this study are called rhythm control and rate control. The rhythm control strategy will attempt to bring the heart beat back to a regular rhythm using treatments known and approved to control heart rhythm. The rate control strategy will attempt to bring the heart rate to less than 100 beats per minute at rest using medications known and recommended to control heart rate. Both strategies are commonly used to treat AF. All of the medications that will be used in this study are the standard of care for use in patients experiencing AF. This research seeks to determine whether rhythm control is better than rate control in patients with AF after cardiac surgery. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02132767
Study type Interventional
Source Icahn School of Medicine at Mount Sinai
Contact
Status Completed
Phase Phase 3
Start date May 2014
Completion date September 2015

See also
  Status Clinical Trial Phase
Recruiting NCT03857711 - Randomized Clinical Trial PULVAB (Prophylactic Pulmonary Veins Ablation) N/A
Recruiting NCT03868150 - Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment Phase 4
Completed NCT01742039 - Prevention of Postoperative Atrial Fibrillation
Recruiting NCT06151652 - Effect of Alpha-Lipoic Acid Supplementation on the Incidence of Postoperative Atrial Fibrillation in Cardiac Surgery Patients Phase 4
Recruiting NCT05076019 - Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement N/A
Completed NCT03646773 - Microvascular Effects of Intravenous Esmolol During Postoperative Atrial Fibrillation
Completed NCT00765089 - Bipolar Radiofrequency Ablation -Role in Prevention of Postoperative Atrial Fibrillation Phase 4
Recruiting NCT05730413 - Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery Phase 4
Completed NCT04307225 - Atrial Fibrillation After CABG and PCI
Completed NCT05009914 - A New Way of Cardiac Denervation to Reduce the Incidence of AF After CABG. N/A
Recruiting NCT03905759 - Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABG Phase 2/Phase 3
Recruiting NCT06054360 - Predictive Value of Right Atrial Strain in Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Recruiting NCT05320705 - The Effect of Intra Operative Dexmedetomidine in Prevention of Early Postoperative Atrial Fibrillation Phase 1
Recruiting NCT05062239 - Post-Operative Atrial Fibrillation After Surgical Aortic Valve Replacement and the Influence of Statins N/A