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Effect of Folic Acid, Vitamin B6 and Vitamin B12 in Diabetic Retinopathy

Proliferative Diabetic Retinopathy Clinical Trial

Clinical Trial Summary

Homocysteine, a well-known inducer of vascular endothelial cell damage has been associated with extracellular matrix changes. Many studies demonstrated that high levels of this aminoacid in diabetic patients increases significantly the risk of the development of this pathology. This study has been undertaken to investigate the role of homocysteine and its cofactors (folic acid, vitamin B6 and B12) during the progression of the diabetic retinopathy.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01921192
Study type Interventional
Source University of Catania
Contact Mariano Malaguarnera, A.P.
Phone +39(0)957262008
Email malaguar@unict.it
Status Recruiting
Phase Phase 4
Start date September 2012
View Details
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