Proliferative Diabetic Retinopathy Clinical Trial
Official title:
A Randomised Control Trial Comparing the Effectiveness of Yellow 577 nm Laser to Conventional Green 532 nm Laser for Proliferative Diabetic Retinopathy
The purpose of this study is to measure effectiveness of yellow 577 nm laser compared to
conventional green laser 532 nm for diabetic retinopathy in terms of number of treatment
sessions required and visual acuity outcome.
The study also compares pain score of patients receiving laser treatment and side effects of
laser treatment.
Diabetes mellitus (DM) is a major medical problem throughout the world. The most common and
potentially most blinding of these complications is proliferative diabetic retinopathy
(PDR).
Panretinal photocoagulation is established as the gold standard of treatment, supported by
the data of the Diabetic Retinopathy Study (DRS).This study found that laser treatment
reduced the rate of severe visual loss by 50%. Currently the green 532nm laser is the most
common wavelength used. However, this conventional green laser has some complications such
as pain, vitreous haemorrhage, choroidal effusion and visual field loss.
Due to the complication of conventional lasers, the yellow laser (577 nm)with peak
absorption of oxyhemoglobin and good absorption of melanin is postulated to be more
effective at producing retinal laser burns with a lower power and less pain compared to the
green laser.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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