Esophageal Squamous Intraepithelial Neoplasia Clinical Trial
Official title:
Detection of Early Esophageal Squamous Neoplasia by Using Virtual Chromoendoscopy and Probe-based Confocal Laser Endomicroscopy
The aim of the present study:
1. To investigate the diagnosing value of pCLE for early esophageal squamous neoplasia.
2. To assess the detection rate of early esophageal squamous neoplasia by virtual
chromoendoscopy
Status | Recruiting |
Enrollment | 200 |
Est. completion date | December 2013 |
Est. primary completion date | December 2013 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 50 Years to 80 Years |
Eligibility |
Inclusion Criteria: - Patients aged between 50 and 80 years old - Patients undergo screening endoscopy or histologically verified esophageal squamous intraepithelial neoplasia before. Exclusion Criteria: - Advanced esophageal, gastric or duodenal cancer - History of upper GI tract surgery - Coagulopathy or acute GI bleeding - Pregnant or breast-feeding (for females) - Impaired renal function - Allergy to fluorescein sodium - Inability to provide informed consent. |
Observational Model: Cohort, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
China | Department of Gastroenterology, Qilu Hospital, Shandong University | Jinan | Shandong |
Lead Sponsor | Collaborator |
---|---|
Shandong University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The diagnostic accuracy of pCLE on early esophageal squamous neoplasia | Patients will be prospectively recruited to evaluate the diagnostic sensitivity, specificity and accuracy of early esophageal squamous neoplasia by using probe-based confocal laser endomicroscopy | 6 month | No |