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Phase II Study of Preoperative IMRT Combined With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer

Locally Advanced Malignant Neoplasm Clinical Trial

Official title:
Phase II Study of Preoperative IMRT Combined With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer

Clinical Trial Summary

Pathological complete response, (pCR) correlates with a favourable overall prognosis in locally advanced rectal cancer patients underwent preoperative chemoradiation, so obtaining a pCR might be beneficial. The aim of the study is to investigate safety and efficacy of preoperative IMRT combined with bevacizumab and capecitabine. primary endpoint is pathological complete remission rate.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

  • Locally Advanced Malignant Neoplasm
  • Neoplasms
Clinical Trial Details
NCT number NCT01871363
Study type Interventional
Source Chinese Academy of Medical Sciences
Contact Jing Jin, professor
Phone 87788280
Email jingjin1025@163.com
Status Recruiting
Phase Phase 2
Start date October 2012
View Details
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