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Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome (MDS) Clinical Trial

Official title:
A Phase II Study Evaluating the Oral Smoothened Inhibitor PF-04449913 in Patients With Myelodysplastic Syndrome (MDS)

Clinical Trial Summary

This study is being done to see how safe an investigational drug is and test how well it will work to help people with refractory/relapsed myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML).

Clinical Trial Description

The main purpose of this study is to see whether the participant's disease responds favorably to the investigational drug, PF-04449913. Post treatment Phase: After coming off of active treatment study drug (PF-04449913), participants will be followed monthly for survival only. No other data will be captured during this time. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01842646
Study type Interventional
Source H. Lee Moffitt Cancer Center and Research Institute
Contact
Status Completed
Phase Phase 2
Start date August 29, 2013
Completion date June 10, 2021
View Details
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