The Prognostic Assessment of Extubation in Aged Patients With Multiple Organ Dysfunction Syndrome

Multiple Organ Dysfunction Syndrome Clinical Trial

Official title:

Key Technology Research of the Comprehensive Treatment of Multiple Organ Dysfunction Syndrome

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01802983
• Other study ID #: 2013670808
• Status: Recruiting
• Phase: N/A
• First received: February 27, 2013
• Last updated: March 1, 2013
• Start date: January 2009
• Est. completion date: December 2013

Study information

• Verified date: February 2013
• Source: Chinese PLA General Hospital
• Contact: Xiao Kun, doctor
• Phone: +8613716608331
• Email: xiaok301[@]163.com
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Observational

Clinical Trial Summary

The multiple organ dysfunction syndrome (MODS) has remained the major factor contributing to prolongation of intensive and mortality. It is reported that the mortality rates have varied between 20% and 100%, depending on number, severity, duration, type and combination, and definition of dysfunction. In our study, the investigators explore some comprehensive treatment technology to improved outcomes of MODS patients.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1
• Est. completion date: December 2013
• Est. primary completion date: December 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• age > 60 years old;

• presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention;

• have trachea intubation after admitting to intensive care unit within 24 hours.

Exclusion Criteria:

• end stage multiple organ failure.

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Multiple Organ Dysfunction Syndrome
• Multiple Organ Failure
• Syndrome

Locations

Country	Name	City	State
China	Chinese PLA General Hospital	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Chinese PLA General Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the prognostic assessment of aged patients with MODS	According to the outcomes of 28-day,all the enrolled patients were divided into survival group and death group, clinical datum of which were collected and analysed. And then these prognosis were evaluated with the current scoring systems [(Acute Physiology and Chronic Health Evaluation?(APACHE?, APACHE ?), Sample Acute Physiological score(SAPS?), Multiple Organ Dysfunction score(MODS)], the predictive power of which were compared by receiver operating characteristic(ROC) curve. Finally, a binary logistic regression analysis was performed to evaluate the concerning prognostic factors of MODSE.	28 days	No