ST Elevated Myocardial Infarction Clinical Trial
Official title:
Observational Study of N/L Ratio in Patients With STEMI
Although the pre-procedural neutrophil to lymphocyte ratio (N/L) has been associated with adverse outcomes among patients with coronary artery disease, its role during the acute phase of ST-segment elevation myocardial infarction (STEMI) has not been fully investigated. This study sought to investigate the association of the pre-procedural N/L ratio within-hospital and long-term outcomes among STEMI patients undergoing primary percutaneous coronary intervention (PCI).
Inflammation plays a role in the initiation and progression of the atherosclerotic process.
Due to a growing recognition of its role, recent studies have focused on inflammatory
markers and their association with outcomes in patients with ST-segment elevation myocardial
infarction (STEMI). Recently, our single center study demonstrated that preprocedural
neutrophil/lymphocyte (N/L) ratio is an independent predictor of impaired coronary flow
after primary percutaneous coronary intervention (PCI) and of in-hospital major advanced
cardiac events (MACE) in patients with STEMI.Several previous studies also evaluated the
role of N/L ratio in long-term outcomes among patients with STEMI; however, they evaluated
the association between long-term mortality and in-hospital N/L ratio, they were
single-center studies and they evaluated a relatively small study population.
In the present multicenter experience, the investigators aimed to investigate the
association of the preprocedural N/L ratio with the in-hospital and long-term outcomes in
patients with STEMI undergoing primary PCI.
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Observational Model: Cohort, Time Perspective: Prospective
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